Status:

RECRUITING

Safety and Efficacy of Lactobacillus Plantarum for Psoriasis: A Randomized Double-Blind Placebo-Controlled Trial

Lead Sponsor:

Shenzhen People's Hospital

Conditions:

Psoriasis

Lactobacillus Plantarum

Eligibility:

All Genders

16-60 years

Phase:

PHASE2

Brief Summary

A growing body of evidence indicates that the pathogenesis of psoriasis may be closely linked to skin microbiome dysbiosis. Compared with healthy individuals, the composition and function of the skin ...

Eligibility Criteria

Inclusion

  • Reference to Psoriasis Area and Severity Index (PASI) score \< 10 Patients have been informed of the study details, voluntarily participate, and have signed the informed consent form; Aged 18-60 years with good general health status; No use of any medications within 6 months; No various inflammatory or immune skin diseases, no local infections, and no neuromuscular diseases.

Exclusion

  • Patients with other types of psoriasis or severe psoriasis; Those in the active phase of skin diseases or with other serious diseases; Other situations deemed unsuitable for enrollment by the researchers, such as subjects who are untrustworthy, unable to accept or understand the study assessments.

Key Trial Info

Start Date :

December 15 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2026

Estimated Enrollment :

184 Patients enrolled

Trial Details

Trial ID

NCT07194200

Start Date

December 15 2025

End Date

June 30 2026

Last Update

December 24 2025

Active Locations (1)

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1

Shenzhen People's Hospital

Shenzhen, Guangdong, China

Safety and Efficacy of Lactobacillus Plantarum for Psoriasis: A Randomized Double-Blind Placebo-Controlled Trial | DecenTrialz