Status:
COMPLETED
Effect of Locally Applied Simvastatin Gel on Dental Implant Stability and Marginal Bone Level
Lead Sponsor:
Maha Zuhair
Conditions:
Dental Implants , Osseointegration , Marginal Bone Loss , Implant Stability
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
stability and marginal bone level. Forty-two patients received dental implants and were randomly assigned to two groups. In the test group, 1.2% simvastatin in 4% methylcellulose gel was applied aroun...
Detailed Description
ental implant stability is a key factor for the long-term success of implant therapy. Stability depends initially on primary mechanical fixation and later on secondary biological osseointegration. Var...
Eligibility Criteria
Inclusion
- Healthy patients ≥ 18 years of either gender.
- Having missing teeth in maxillary jaw maxillary jaw( premolar and molar area) at least 6 months after teeth extraction.
- Patients who had alveolar ridges of sufficient vertical and horizontal dimensions and were considered surgically straight forward cases according to SAC classification
Exclusion
- Patients with signs of acute or chronic infection in the implant zone
- Patients with signs of parafunctional habits
- Patients with history of systemic diseases or recent radiotherapy to the head and neck or chemotherapy.
- Patients who had history or were currently under treatment with oral or intravenous bisphosphonate or statins other drugs that may alter bone metabolism
- Patients who are heavy smoker or presented with severe periodontitis.
- Pregnant patients.
Key Trial Info
Start Date :
October 3 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 6 2025
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT07194447
Start Date
October 3 2024
End Date
July 6 2025
Last Update
September 26 2025
Active Locations (1)
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1
College of Dentistry, University of Baghdad
Baghdad, Baghdad Governorate, Iraq, 10071