Status:

NOT_YET_RECRUITING

Feasibility Trial of Combination of Obstetrical Carrier Screening and Hereditary Cancer Screening

Lead Sponsor:

Columbia University

Collaborating Sponsors:

Natera, Inc.

Conditions:

Hereditary Cancer Syndrome

Eligibility:

FEMALE

18-55 years

Phase:

NA

Brief Summary

The investigators hypothesize that preconception and pregnancy may be a feasible and effective time to offer inherited cancer risk screening. This study will assess interest in cancer genetic testing ...

Detailed Description

In this prospective trial, a clinician in the department of OBGYN will meet with preconception/pregnant patients who are undergoing obstetrical carrier screening (OCS) at Columbia University affiliate...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Age: 18 years - 55 years
  • Patients receiving obstetrical-related care at a CUMC-affiliated enrollment site
  • Patients who have elected to undergo OCS with the CUMC-affiliated obstetrics provider
  • Patients with prior OCS but planned to repeat OCS are eligible
  • Patients can speak and read in English or Spanish
  • Exclusion criteria:
  • Patients who have previously completed a multigene hereditary cancer syndrome panel
  • Patients that have a hematologic cancer or hematologic pre-cancer
  • Patients who have a history of an autologous bone marrow transplant

Exclusion

    Key Trial Info

    Start Date :

    December 1 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 31 2028

    Estimated Enrollment :

    1000 Patients enrolled

    Trial Details

    Trial ID

    NCT07195071

    Start Date

    December 1 2025

    End Date

    December 31 2028

    Last Update

    October 29 2025

    Active Locations (1)

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    Columbia University Irving Medical Center

    New York, New York, United States, 10032

    Feasibility Trial of Combination of Obstetrical Carrier Screening and Hereditary Cancer Screening | DecenTrialz