Status:

COMPLETED

CYFIP1 and PKM2 Synergistically Regulate ROS and Glycolysis in Colorectal Cancer Through the AKT/mTOR/HIF-1α Cascad

Lead Sponsor:

hui hou

Conditions:

Colorectal Cancer (CRC)

Specimens Are to be Collected From Subjects Who Are Having or Have Had a Fluid or Tissue Removed, a Biopsy or a Blood or Bone Marrow Draw

Eligibility:

All Genders

Brief Summary

Collect some tumor tissue specimens from patients who have undergone colorectal cancer surgery and conduct experiments such as immunohistochemistry to observe the expression of related genes in colore...

Detailed Description

We need to collect postoperative specimens and adjacent normal tissue specimens from patients with colorectal cancer for immunohistochemical staining. There is no need to conduct any other grouping of...

Eligibility Criteria

Inclusion

  • (1) Patients diagnosed with colorectal cancer who received surgical treatment and postoperative chemotherapy (2) Patients who were conscious of their condition and voluntarily participated (3) No other serious underlying diseases

Exclusion

  • (1) Concurrent other serious chronic diseases or organ damage (2) Diagnosed with benign colorectal tumors

Key Trial Info

Start Date :

August 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 1 2025

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT07197151

Start Date

August 1 2022

End Date

September 1 2025

Last Update

September 29 2025

Active Locations (1)

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The Second Affiliated Hospital of Anhui Medical University

Hefei, Anhui, China, 230032