Status:
ENROLLING_BY_INVITATION
Comparison of Inter-appointment Pain Reduction During Root Canal Treatment in Symptomatic Apical Periodontitis by Using Intracanal Medicaments; Chlorhexidine Gel and Single Antibiotic Paste Nitrofurantoin
Lead Sponsor:
Altamash Institute of Dental Medicine
Conditions:
Intracanal Medicament
Eligibility:
All Genders
16-45 years
Phase:
PHASE1
PHASE2
Brief Summary
This study is being conducted to find out which of two medications-Chlorhexidine Gel or Nitrofurantoin-works better in reducing pain between root canal treatment visits. Sometimes, patients with infec...
Detailed Description
This randomized controlled trial is designed to evaluate and compare the efficacy of two commonly used intracanal medicaments-2% Chlorhexidine Gel and Single Antibiotic Paste (Nitrofurantoin)-in reduc...
Eligibility Criteria
Inclusion
- Patients with single rooted permanent teeth of both arches.
- Patients with a pulpal status of necrosis with or without periapical radiolucency, confirmed using Electric Pulp Test (EPT) and Cold Test.
- Male and female patients age of 16 to 45 yrs.
- Patients of both genders.
Exclusion
- Patients with uncontrolled diabetes.
- Presence of periapical granuloma or cyst confirmed via radiographic evaluation.
- Patient is on any medication that affects pain, inflammation and infection like analgesic, antibiotics since last 7 days
- Patient requiring endodontic re-treatment.
- Patients with immature teeth with open apices.
- Patients with calcified canals.
Key Trial Info
Start Date :
May 20 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 30 2025
Estimated Enrollment :
220 Patients enrolled
Trial Details
Trial ID
NCT07198919
Start Date
May 20 2025
End Date
November 30 2025
Last Update
September 30 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
AIDM
Karachi, Sindh, Pakistan, 74500