Status:

RECRUITING

Boosting Microbiota Butyrate Producers to Improve Gut Health

Lead Sponsor:

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Conditions:

Adults 20 to 80 Years

Eligibility:

All Genders

20-80 years

Brief Summary

The human gut microbiota is a dynamic ecosystem essential to health, influenced by diet, age, and lifestyle. It plays a key role in digestion, immunity, and nervous system regulation. Among its import...

Detailed Description

The human gut microbiota is a complex and adaptable ecosystem closely linked to its host, influenced by factors such as diet, lifestyle, and age. It plays key roles in nutrition, immunity, and pathoge...

Eligibility Criteria

Inclusion

  • People between the ages of 20 and 80, in good health, with a body mass index between 18.5 kg/m² and 30 kg/m², who are not deprived of their liberty or under guardianship.
  • Additional criteria for people aged between 20 and 60: Engaging in sports at least twice a week or following a flexitarian diet, No known chronic conditions, Not undergoing chronic treatment.

Exclusion

  • Under the age of 20 or over the age of 80, Part of the principal investigator's team, Reporting to the investigator (intern, student, or employee under their authority), Having been on antibiotic therapy in the 3 months prior to sampling, Having taken probiotics in the 15 days prior to sampling, Having taken synbiotics in the 15 days prior to sampling, Having a BMI below 18.5 kg/m² or above 30 kg/m², Being deprived of liberty or under guardianship.
  • Additional criteria for people aged between 20 and 60: Not exercising twice a week or following a flexitarian diet, Having a chronic illness, Undergoing chronic treatment

Key Trial Info

Start Date :

November 24 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2028

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT07198984

Start Date

November 24 2025

End Date

November 1 2028

Last Update

December 16 2025

Active Locations (1)

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1

INRAE

Jouy-en-Josas, France, 78350