Status:

NOT_YET_RECRUITING

Clinical validatiOn of an AI-based DEcision Support System for Robotic Upper Limb Rehabilitation in Patients With Stroke. A CO-AIDER Study.

Lead Sponsor:

Fondazione Don Carlo Gnocchi Onlus

Collaborating Sponsors:

Fondazione Policlinico Universitario Campus Bio-Medico

Scuola Superiore Sant'Anna di Pisa

Conditions:

Stroke

Stroke Ischemic

Eligibility:

All Genders

18-85 years

Phase:

NA

Brief Summary

The goal of this clinical trial is to validate an artificial intelligence-based decision support system (AI-DSS) for robotic rehabilitation in participants with stroke. The study aims to answer the f...

Detailed Description

The CO-AIDER study is a multicenter, randomized, controlled, two-arm, non-profit clinical trial validating an AI-based decision support system (AI-DSS) in robotic upper limb rehabilitation for stroke ...

Eligibility Criteria

Inclusion

  • Diagnosis of ischemic or hemorrhagic stroke confirmed by Computed Tomography (CT) or Magnetic Resonance Imaging (MRI);
  • Age between 18 and 85 years;
  • Time since stroke less than six months;
  • Mild to severe upper limb impairment (Fugl-Meyer Assessment for Upper Extremity (FMA-UE) ≤ 58).

Exclusion

  • Behavioral or cognitive disorders and/or reduced compliance;
  • Severe spasticity or hypertonia in the affected limb (Modified Ashworth Scale (MAS) \> 3);
  • Severe visual impairments;
  • Concurrent participation in another clinical trial for upper limb rehabilitation following stroke;
  • Refusal to provide written informed consent.

Key Trial Info

Start Date :

September 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT07199322

Start Date

September 1 2025

End Date

December 1 2026

Last Update

September 30 2025

Active Locations (10)

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Page 1 of 3 (10 locations)

1

Fondazione Don Carlo Gnocchi, Polo Specialistico Riabilitativo

Sant'Angelo dei Lombardi, AV, Italy, 83054

2

Fondazione Don Carlo Gnocchi, Centro Spalenza

Rovato, BS, Italy, 25038

3

IRCSS Fondazione Don Carlo Gnocchi

Florence, FI, Italy, 50143

4

Fondazione Don Carlo Gnocchi, Polo Specialistico Riabilitativo

Tricarico, Mount, Italy, 75019