Status:
NOT_YET_RECRUITING
Dexmedetomidine Versus Magnesium Sulfate Infusion in Craniotomy
Lead Sponsor:
Assiut University
Conditions:
Craniotomy Surgery
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
To compare the intraoperative effects of Dexmedetomidine and Magnesium Sulfate infusion on intracranial pressure and cerebral perfusion pressure in adult patients undergoing craniotomy
Detailed Description
Intracranial pressure (ICP) and cerebral perfusion pressure (CPP) are critical parameters in craniotomy patients . Effective modulation of these pressures during surgery can improve intraoperative sta...
Eligibility Criteria
Inclusion
- Age 18-65 years
- Elective craniotomy for supratentorial pathology
- No contraindication to lumbar drain insertion
- Baseline mental status is stable, allowing for a reliable postoperative neurological evaluation can be done
- ASA physical status I-III
Exclusion
- Coagulopathy or current anticoagulation
- Severe renal or hepatic dysfunction
- Known allergy to study medications
- traumatic brain injury
Key Trial Info
Start Date :
October 20 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT07199595
Start Date
October 20 2025
End Date
November 1 2026
Last Update
September 30 2025
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