Status:
ACTIVE_NOT_RECRUITING
Chewing Gum vs. Ondansetron as Rescue Treatment for PONV in Female Patients
Lead Sponsor:
Makassed General Hospital
Conditions:
Postoperative Nausea and Vomiting (PONV)
Eligibility:
FEMALE
18+ years
Phase:
PHASE1
Brief Summary
The proposed randomized clinical trial aims to test and compare the efficacy of chewing gum vs. Intravenous antiemetic ondansetron as rescue treatment for post-operative nausea and vomiting (PONV) amo...
Detailed Description
Post-operative nausea and vomiting remains a significant complication following general anesthesia, particularly when volatile anesthetics are used. Previous studies, including a multicenter randomize...
Eligibility Criteria
Inclusion
- Females
- Aged 18 and above,
- Weight 40kg and above,
- Who have undergone laparoscopic
- Surgery under volatile anesthetic-based general anesthesia.
Exclusion
- Have history of motion sickness,
- Maintained anesthesia during surgery using Propofol-pump
- Were given antiemetics within 8 hours pre-surgery
- Allergy to ondansetron
- Planned mechanical ventilation post-operation
Key Trial Info
Start Date :
August 22 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 28 2026
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT07201883
Start Date
August 22 2025
End Date
February 28 2026
Last Update
October 1 2025
Active Locations (1)
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1
Makassed General Hospital
Beirut, Lebanon