Status:
COMPLETED
Ozone-therapy in Non-surgical Periodontal Therapy
Lead Sponsor:
Universita di Verona
Conditions:
Ozone-therapy (O3)
Periodontitis
Eligibility:
All Genders
18-84 years
Phase:
NA
Brief Summary
Non-surgical periodontal therapy is a widely adopted procedure for the treatment of periodontitis, particularly in its moderate to severe stages. The approach involves the mechanical and manual debrid...
Eligibility Criteria
Inclusion
- Age between 18 and 84 years; Good general health status; Diagnosis of severe periodontitis involving at least 30% of all teeth, with at least three non-adjacent teeth presenting three sites with probing pocket depth (PPD) greater than 4 mm in at least two quadrants, and having lost at least four teeth due to periodontitis; Presence of at least 16 teeth, with a minimum of four teeth per quadrant.
Exclusion
- Pregnancy or breastfeeding; Presence of decompensated systemic diseases that may compromise the outcomes of the study or the patient's health; Regular use of antibiotics; Regular use of anti-inflammatory drugs (NSAIDs, corticosteroids, or aspirin); Use of anticoagulant medications; History of systemic antibiotic therapy within six months prior to enrollment; History of any periodontal therapy within six months prior to enrollment; Presence of severe mental or cognitive disorders.
Key Trial Info
Start Date :
August 3 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 30 2024
Estimated Enrollment :
39 Patients enrolled
Trial Details
Trial ID
NCT07202312
Start Date
August 3 2023
End Date
May 30 2024
Last Update
October 1 2025
Active Locations (1)
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1
Alessia Pardo
Verona, Italy, Italy, 37134