Status:

COMPLETED

The Effectiveness of Intracuff Dexmedetomidine in Preventing Postoperative Sore Throat Following Prone Surgery

Lead Sponsor:

Prince Sultan Military Medical City

Conditions:

Sore Throat

Eligibility:

All Genders

18-75 years

Phase:

PHASE2

Brief Summary

Postoperative sore throat (POST) is a common consequence of tracheal intubation, affecting 30% to 65% of patients, while hoarseness occurs in approximately 16% to 55% of cases. POST is undesirable as ...

Detailed Description

One hundred patients aged between 18 and 75 years, American Society of Anesthesiologists (ASA) physical status I and II patients of either sex, undergoing lumbar spine surgery in the prone position un...

Eligibility Criteria

Inclusion

  • Patients aged between 18 to 75 years
  • American Society of Anesthesiologists (ASA) physical status I and II patients
  • Either sex
  • Undergoing lumbar spine surgery in prone position under general anesthesia with endotracheal intubation.

Exclusion

  • Patients with a history of recent respiratory tract infection
  • Prior medication with analgesics or corticosteroids.
  • Patients who have preoperative sore throat, hoarseness and cough, have a nasogastric tube,
  • Patients with Mallampati class \> 2 and who required more than one attempt for tracheal intubation or patients had a duration of tracheal intubation of \< 60 min or \> 300 min and
  • Patients not willing to provide their voluntary written informed consent.

Key Trial Info

Start Date :

February 10 2025

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2025

Estimated Enrollment :

4 Patients enrolled

Trial Details

Trial ID

NCT07202624

Start Date

February 10 2025

End Date

October 1 2025

Last Update

November 20 2025

Active Locations (1)

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Prince Sultan Military Medical City

Riyadh, Saudi Arabia, 12232