Status:
NOT_YET_RECRUITING
The Predictive Value of Multimodal Brain Monitoring for Perioperative Stroke in Cardiac Surgery Patients
Lead Sponsor:
Beijing Tiantan Hospital
Conditions:
Multimodal Monitoring
Perioperative Stroke
Eligibility:
All Genders
18+ years
Brief Summary
Postoperative stroke following cardiac surgery is associated with a ninefold increase in mortality risk compared to patients without stroke. Perioperative monitoring in cardiac surgery involves a rang...
Eligibility Criteria
Inclusion
- Patients scheduled for elective cardiac surgery
- Presence of at least one of the following high-risk factors for stroke: a.Peripheral vascular disease (history of peripheral artery bypass grafting, amputation for ischemia, Ankle-Brachial Pressure Index \< 0.9, or history of abdominal aortic aneurysm repair).b.Cerebrovascular disease (history of stroke, transient ischemic attack, or carotid stenosis \>70%).c.Renal insufficiency (Glomerular Filtration Rate \< 60 mL/min/1.73m²).d.Diabetes mellitus (requiring oral hypoglycemic agents and/or insulin therapy).e.Urgent coronary artery bypass grafting (inpatient requiring revascularization due to acute coronary syndrome or myocardial infarction).f.Recent smoking history (within 1 year).g.Left ventricular ejection fraction \< 35%
- Provision of signed informed consent
Exclusion
- Contraindication to magnetic resonance imaging (e.g., claustrophobia, inability to lie flat for the duration of the study, presence of a pacemaker or implantable cardioverter-defibrillator, or other metallic implants)
- Inability to complete cognitive function assessments
- Patients with psychiatric, legal disabilities or under legal guardianship
- Life expectancy of less than 3 months
- Women who are lactating or pregnant
- Diagnosis of any type of dementia
Key Trial Info
Start Date :
October 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2028
Estimated Enrollment :
369 Patients enrolled
Trial Details
Trial ID
NCT07202689
Start Date
October 1 2025
End Date
December 31 2028
Last Update
October 2 2025
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