Status:
RECRUITING
Effect of Neoadjuvant Chemotherapy on MRI Accuracy Before Cystectomy
Lead Sponsor:
Assiut University
Conditions:
Muscle Invasive Bladder Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this clinical trial is to learn if neoadjuvant chemotherapy (NAC) affects the accuracy of magnetic resonance imaging (MRI) in staging muscle-invasive bladder cancer (MIBC). This study will...
Eligibility Criteria
Inclusion
- Patients diagnosed with cT2 urothelial carcinoma of the urinary bladder, according to the TNM classification, who give informed, written consent on participation in the study and approve all its requirements.
Exclusion
- Patients who have received pelvic radiotherapy.
- Previous open or laparoscopic pelvic surgery.
- Patients with contraindications to MRI.
- Patients who are unfit for or refuse radical cystectomy.
- Ineligibility to cisplatin.
- squamous differentiation in the histopathology
Key Trial Info
Start Date :
September 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 20 2026
Estimated Enrollment :
76 Patients enrolled
Trial Details
Trial ID
NCT07202819
Start Date
September 1 2025
End Date
August 20 2026
Last Update
October 2 2025
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Urology Department, Faculty of Medicine, Assiut University
Asyut, Asyut Governorate, Egypt, 71515
2
Urology Department, Faculty of Medicine, Assiut University
Asyut, Asyut Governorate, Egypt, 71515