Status:

NOT_YET_RECRUITING

Biopsychosocial Factors and Muscle Morphology After a Resistance Exercise

Lead Sponsor:

University of Central Florida

Conditions:

Low Back Pain, Chronic

Eligibility:

All Genders

18-50 years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate the longitudinal effects of a four-week dynamic resistance training program using the 45-degree Roman chair on pain sensitivity changes after exercise and lumb...

Eligibility Criteria

Inclusion

  • chronic low back pain lasting ≥ 12 weeks
  • current pain intensity ≥ 3/10 but no higher than an 8/10 on the Numeric Pain Rating Scale (NPRS) within the past 48 hours
  • resistance trained (defined as 2x/week for the past 8-12 weeks)
  • able to read and speak English for informed consent and completion of questionnaires
  • willing and physically able to complete all testing and intervention sessions.

Exclusion

  • History of spinal surgery, fusion, or fracture within the past 6 months
  • diagnosed degenerative disc disease, scoliosis, or spinal pathology that precludes safe exercise participation
  • use of an assistive device for walking (cane, walker) within the past year
  • pregnancy, due to contraindications for exercise testing and ultrasound -body weight ≥ 300 lbs., which exceeds the safe capacity of the Roman chair --
  • current tobacco/nicotine use
  • current enrollment in physical therapy or structured rehabilitation for LBP,
  • cardiovascular, pulmonary, metabolic, or systemic disease that increases risk during exercise
  • nociplastic pain conditions (e.g., fibromyalgia) or neurological conditions that confound EIH responses
  • inability to complete ≥ 8 Roman chair repetitions with proper form during screening
  • non-English speaking

Key Trial Info

Start Date :

October 20 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 20 2026

Estimated Enrollment :

22 Patients enrolled

Trial Details

Trial ID

NCT07203430

Start Date

October 20 2025

End Date

October 20 2026

Last Update

October 2 2025

Active Locations (1)

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1

University of Central Florida

Orlando, Florida, United States, 32816