Status:

COMPLETED

AI-Assisted Acute Myeloid Leukemia Evaluation With the Leukemia End-to-End Analysis Platform (LEAP) Versus Clinician-Only Assessment

Lead Sponsor:

Harvard Medical School (HMS and HSDM)

Collaborating Sponsors:

National Taiwan University Hospital

Far Eastern Memorial Hospital

Conditions:

Acute Promyelocytic Leukemia (APL)

Acute Myeloid Leukaemia (AML)

Eligibility:

All Genders

Phase:

NA

Brief Summary

This study will test whether artificial intelligence (AI) can help doctors diagnose a rare blood cancer called acute promyelocytic leukemia (APL) more quickly and accurately. Doctors usually examine b...

Detailed Description

This study aims to evaluate the effect of artificial intelligence (AI) assistance on clinicians' diagnostic performance in detecting acute promyelocytic leukemia (APL) using Wright-Giemsa-stained bone...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for Pathology Slides (i.e., Cases):
  • Wright-Giemsa-stained bone marrow aspirate smears
  • Final diagnosis confirmed through molecular testing in conjunction with expert pathology evaluation
  • Exclusion Criteria for Pathology Slides (i.e., Cases):
  • Poor-quality or unreadable slides
  • Cases used in AI training
  • Inclusion Criteria for Readers (i.e., Participants):
  • Board-certified or board-eligible pathologists, or board-certified/board-eligible hematologists who routinely make hematopathology diagnoses in their clinical practice
  • Willingness to complete both unaided and AI-assisted review sessions

Exclusion

    Key Trial Info

    Start Date :

    September 9 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    October 10 2025

    Estimated Enrollment :

    10 Patients enrolled

    Trial Details

    Trial ID

    NCT07203885

    Start Date

    September 9 2025

    End Date

    October 10 2025

    Last Update

    October 31 2025

    Active Locations (1)

    Enter a location and click search to find clinical trials sorted by distance.

    Page 1 of 1 (1 locations)

    1

    Harvard Medical School

    Boston, Massachusetts, United States, 02115