Status:
NOT_YET_RECRUITING
IVC Ultrasound Versus Central Venous Pressure for Early Detection of Hypovolemia in Shock Patients
Lead Sponsor:
Assiut University
Conditions:
Shock
Hypovolemia
Eligibility:
All Genders
18-65 years
Brief Summary
This study aims to compare ultrasound-guided inferior vena cava (IVC) assessment with central venous pressure (CVP) monitoring for the detection of hypovolemia in shock patients in the emergency depar...
Detailed Description
Hypovolemia is a major contributor to morbidity and mortality among patients presenting with shock in the emergency department. Early recognition and accurate assessment of intravascular volume status...
Eligibility Criteria
Inclusion
- 1- Adult patients aged ≥18 years. 2.Both male and female patients will be included in the study. 3. Presentation to the Emergency Department with clinical evidence of shock, defined by: Hypotension (systolic blood pressure \<90 mmHg or mean arterial pressure \<65 mmHg).
- Evidence of tissue hypoperfusion (e.g., altered mental status, cold extremities, or oliguria).
- Elevated serum lactate (\>2 mmol/L). 4. Shock attributed to hypovolemic, septic, or hemorrhagic etiologies. 5. Patients requiring fluid resuscitation and hemodynamic monitoring.
Exclusion
- 1 - Patients younger than 18 years. 2. Pregnancy. 3.Cardiogenic or obstructive shock (e.g., cardiac tamponade, massive pulmonary embolism, or tension pneumothorax).
- Known inferior vena cava (IVC) anomalies (e.g., congenital absence, thrombosis).
- 5\. Increased intra-abdominal pressure or severe ascites. 6. Morbid obesity (BMI ≥40 kg/m²) or any condition interfering with adequate IVC ultrasound visualization.
- 7\. Prior central venous catheterization performed before Emergency Department arrival.
- 8\. Congestive heart failure (CHF) with left ventricular ejection fraction (LVEF \<40%) or pulmonary hypertension.
- 9\. Refusal of the patient or legal guardian to participate in the study.
Key Trial Info
Start Date :
December 15 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 15 2026
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT07206732
Start Date
December 15 2025
End Date
December 15 2026
Last Update
November 19 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Emeregency medicine department ,Assiut University
Asyut, Sahel Selim, Egypt