Status:
COMPLETED
Analysis of Integrated Clinical, Laboratory and Prognostic Data of Neonates With Necrotizing Enterocolitis
Lead Sponsor:
Sixth Affiliated Hospital, Sun Yat-sen University
Conditions:
Necrotizing Enterocolitis
Eligibility:
All Genders
1-3 years
Brief Summary
This is a retrospective study led by The Sixth Affiliated Hospital, Sun Yat-sen University, focusing on newborns diagnosed with necrotizing enterocolitis (NEC)-a serious gastrointestinal disease that ...
Detailed Description
1. Study Rationale Necrotizing Enterocolitis (NEC) is a life-threatening gastrointestinal disorder primarily affecting very low birth weight (VLBW) neonates (incidence: 5-12%). Around 20-40% of cases ...
Eligibility Criteria
Inclusion
- (1) Diagnosis of NEC and having undergone surgical treatment, confirmed by clinical manifestations (e.g., abdominal distension, bloody stools), radiological evidence (pneumatosis intestinalis, portal venous gas, or pneumoperitoneum), and pathological examination in accordance with established guidelines; (2) Availability of complete medical records for data extraction.
Exclusion
- (1) Congenital gastrointestinal malformations (e.g., intestinal atresia, Hirschsprung's disease) or spontaneous intestinal perforation; (2) Hereditary metabolic disorders; (3) Incomplete clinical data or refusal of participation.
Key Trial Info
Start Date :
January 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 18 2025
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT07207915
Start Date
January 1 2023
End Date
September 18 2025
Last Update
October 6 2025
Active Locations (1)
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1
The Sixth Affiliated Hospial, Sun Yat-sen University
Guangzhou, Guangdong, China, 510655