Status:
RECRUITING
Intravenous Infusion of Umbilical Cord Blood as an Adjunctive Treatment for Alzheimer's Disease
Lead Sponsor:
Anhui Provincial Hospital
Collaborating Sponsors:
Shandong Qilu Stem Cell Engineering Co., Ltd.
Conditions:
Alzheimer Disease (AD)
Eligibility:
All Genders
50-75 years
Phase:
EARLY_PHASE1
Brief Summary
This study is a single-center, prospective, double-blind, randomized controlled clinical trial (RCT). Employing a parallel-group design, the trial plans to enroll 30 clinically diagnosed AD patients,...
Eligibility Criteria
Inclusion
- Age range: 50 - 75 years old, gender not restricted;
- Patients diagnosed with Alzheimer's disease (AD) according to the AT(N) diagnostic framework (with positive amyloid protein PET test results);
- MMSE score between 15 and 30 points, patients with mild to moderate Alzheimer's disease;
- The patient has a fixed caregiver who is willing to accompany the patient throughout the corresponding program;
- The patient has a literacy level above primary school, sufficient to complete the tests stipulated in the program;
- The patient or the guardian consents to participate in this clinical trial voluntarily and signs the informed consent form.
Exclusion
- Dementia caused by other diseases, such as vascular dementia, frontotemporal dementia, and Lewy body dementia, etc.;
- The patient has other major systemic diseases, malignant tumors, chronic obstructive pulmonary disease or pulmonary fibrosis, etc. related to the lungs;
- The patient's white blood cell and neutrophil levels are below the normal lower limit;
- The patient has active infectious diseases, such as syphilis, AIDS, hepatitis B, hepatitis C;
- The patient has a history of stroke, epilepsy, alcohol abuse, or abuse of psychotropic drugs;
- Severe visual or hearing impairment, or those who cannot complete the relevant assessment due to other reasons;
- Patients who have participated in other clinical trials within the last 2 months;
- Other situations that the researchers consider not suitable for participating in clinical research.
Key Trial Info
Start Date :
July 31 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT07208344
Start Date
July 31 2025
End Date
June 30 2026
Last Update
October 6 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
The First Affiliated Hospital of the University of Science and Technology of China
Hefei, Anhui, China, 230000