Status:
NOT_YET_RECRUITING
Multi-omics Study of Peritoneal Dialysis Effluent to Explore Biomarkers of Peritoneal Fibrosis
Lead Sponsor:
Shanghai Jiao Tong University School of Medicine
Conditions:
Peritoneal Dialysis
Peritoneal Fibrosis
Eligibility:
All Genders
18-75 years
Brief Summary
Biomarkers of peritoneal fibrosis in patients with peritoneal dialysis were investigated by transcriptomics of exfoliated cells and metabolomics of exfoliated cells in peritoneal dialysis
Detailed Description
This study is a cross-sectional study with no clinical intervention and follow-up. Patients who met the inclusion criteria were enrolled in the study, and demographic indicators and clinical hematolo...
Eligibility Criteria
Inclusion
- Patients on peritoneal dialysis: a. Age 18-75 years; b. Regular abdominal dialysis due to uremia\> 3 months; c. Signed informed consent
- Hemodialysis patients: a. Age 18-75 years; b. Due to regular hemodialysis due to uremia\> 3 months old, allogeneic kidney transplantation is planned; c. Signed informed consent
- Patients with normal renal function: a. Age 18-75 years; b. Proposed elective inguinal hernia repair surgery; c. Signed informed consent.
Exclusion
- Patients on peritoneal dialysis: a. History of peritonitis in the past 3 months; b. History of abdominal tumors with peritoneal metastases
- Hemodialysis patients: a. Previous abdominal dialysis history; b. History of abdominal tumors with peritoneal metastases Patients with normal renal function: a. History of chronic kidney disease; b. History of abdominal tumors with peritoneal metastases
Key Trial Info
Start Date :
October 20 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 30 2026
Estimated Enrollment :
55 Patients enrolled
Trial Details
Trial ID
NCT07208513
Start Date
October 20 2025
End Date
September 30 2026
Last Update
October 6 2025
Active Locations (1)
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1
Renji Hospital
Shanghai, Shanghai Municipality, China