Status:
RECRUITING
Diagnosis Value of Interoceptive EEG Indicators by Rectal Stimulation in DoC
Lead Sponsor:
YiLin Zhao
Collaborating Sponsors:
The Second People's Hospital of Hefei
Conditions:
Disorders of Consciousness
Eligibility:
All Genders
18+ years
Brief Summary
Study on the Significance and Value of Interoception-Related Indicators in the Classification of Patients with Disorders of Consciousness (DoC) via Rectal Stimulation
Detailed Description
Disorders of Consciousness (DoC) represent one of the sequelae of severe brain injuries caused by a variety of etiologies, including traumatic brain injury, stroke, and cardiac arrest. They may also r...
Eligibility Criteria
Inclusion
- Patients with non-acute Disorders of Consciousness (DoC) (disease course ≥ 28 days).
- Aged 18 years or older.
- No symptoms of fever, infection, or other similar conditions within 15 days.
- No use of sedatives within 15 days.
- No use of any drugs that may alter gastrointestinal motility within 7 days prior to testing.
- Family members of participating patients have provided consent and signed the informed consent form.
Exclusion
- Patients with functional impairments caused by developmental psychiatric disorders or neurological diseases.
- Patients with untreated epilepsy.
- Untreated cerebral edema.
- Patients with unstable vital signs.
- A history of intestinal diseases.
- A history of abdominal surgery other than simple appendectomy or simple cholecystectomy.
- Organic diseases such as spinal cord injury, traumatic brain injury, and thyroid dysfunction.
Key Trial Info
Start Date :
December 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT07208942
Start Date
December 1 2024
End Date
December 1 2025
Last Update
October 6 2025
Active Locations (2)
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1
The Second People's Hospital of Hefei
Hefei, Anhui, China, 230000
2
Hangzhou Normal University
Hangzhou, Zhejiang, China, 310000