Status:
NOT_YET_RECRUITING
Acquired Dyslexia Modeling and Treatment
Lead Sponsor:
Rutgers, The State University of New Jersey
Collaborating Sponsors:
National Institute on Deafness and Other Communication Disorders (NIDCD)
Conditions:
Stroke
Dyslexia, Acquired
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
This study is a low-risk, early phase 1, multicenter trial to test the use of a computational (neural network) cognitive model of reading to simulate acquired dyslexia and its treatment. The aim is to...
Eligibility Criteria
Inclusion
- Fluent in English as a first language pre-stroke by self report.
- Normal or corrected-to-normal vision.
- Normal or aided hearing.
- Left hemisphere ischemic or hemorrhagic stroke (as verified by a structural brain scan).
- Impaired reading as confirmed by significant impairment in the Basic Skills cluster of the Woodcock Reading Mastery Test - III.
Exclusion
- Diagnosed pre-stroke neurological disease affecting the brain other than left hemisphere stroke.
- Severe apraxia of speech (determined by consensus judgment among speech-language pathologists).
- History of learning disabilities such as developmental dyslexia or current self-reported major psychiatric disorders.
- Inability to undergo, or provide a copy of, a post-stroke brain imaging scan.
Key Trial Info
Start Date :
November 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2026
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT07209488
Start Date
November 1 2025
End Date
September 1 2026
Last Update
October 7 2025
Active Locations (3)
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1
Florida State University
Tallahassee, Florida, United States, 32306
2
Johns Hopkins University School of Medicine
Baltimore, Maryland, United States, 21287
3
Kessler Foundation
West Orange, New Jersey, United States, 07052