Status:
RECRUITING
Evaluation of Regenerative Endodontic Treatment for Immature Teeth
Lead Sponsor:
Kafrelsheikh University
Conditions:
Pulpal Necrosis
Eligibility:
All Genders
9-15 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to evaluate if regenerative endodontic treatment using two different forms of demineralized dentin matrix (DDM) can effectively treat immature permanent single-roote...
Detailed Description
The study was conducted as a split-mouth randomized clinical trial, approved by research ethics committee, Faculty of Dentistry, Kafrelsheikh University, and carried out at Endodontic Department, Facu...
Eligibility Criteria
Inclusion
- Systemically healthy patients (i.e., free of any systemic diseases).
- Patients presenting with immature permanent single-rooted teeth.
- Age: 9 -15 years.
- Teeth diagnosed as either vital (asymptomatic irreversible pulpitis or symptomatic irreversible pulpitis and the bleeding didn't stop after 5 minutes application of hemostatic agent) or non-vital pulp.
Exclusion
- Patients who are allergic to any drugs used in this study or with systemic illness
- Teeth that are grossly decayed or fractured and require post and core as final restorations
- Presence of periodontal pockets greater than 4 mm.
- Radiographical evidence of apical foramen less than 1 mm.
- Presence of periapical radiolucency exceeding 10 mm.
- Presence of external or internal root resorption.
- Patients with a history of major surgeries like cardiac, kidney transplantation, haemodialysis.
Key Trial Info
Start Date :
September 15 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT07210359
Start Date
September 15 2025
End Date
December 1 2026
Last Update
October 7 2025
Active Locations (1)
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1
KafrelsheikhU
Kafr ash Shaykh, Kafr Elsheikh, Egypt, 33511