Status:
RECRUITING
Optimal PEEP Level for Minimizing the Risk of Postoperative Atelectasis: A Retrospective Cohort Study Based on Lung Ultrasound Monitoring
Lead Sponsor:
State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
Conditions:
Postoperative Pulmonary Complications (PPCs)
Postoperative Atelectasis
Eligibility:
All Genders
18+ years
Brief Summary
Background: After surgery with general anesthesia, it is common for parts of the lungs to collapse, a condition called atelectasis. This can lead to low blood oxygen levels and other lung complication...
Detailed Description
Background and Rationale Postoperative pulmonary complications (PPCs) are a significant cause of morbidity and mortality, associated with a nearly 20% increase in lethality and prolonged hospital stay...
Eligibility Criteria
Inclusion
- Patients undergoing surgical intervention under general anesthesia with mechanical ventilation.
- Airway protection managed with either an endotracheal tube or a laryngeal mask.
- A normal baseline ultrasound of the posterior-basal lung regions, corresponding to a score of 0 on the lung ultrasound scale.
Exclusion
- Patients undergoing cardiac or thoracic surgery.
- Presence of a perioperatively identified pneumothorax.
- Inability to obtain adequate ultrasound visualization of the target lung zones.
- Presence of hydrothorax.
- Confirmed perioperative pulmonary aspiration.
- Presence of any pathological findings on the initial baseline ultrasound of the posterior-basal lung regions.
- Requirement for massive blood transfusion during the operation.
- Patients undergoing surgery on the diaphragm.
- Prolonged residual sedation lasting more than 2 hours post-operation
Key Trial Info
Start Date :
September 22 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 31 2026
Estimated Enrollment :
450 Patients enrolled
Trial Details
Trial ID
NCT07211074
Start Date
September 22 2025
End Date
January 31 2026
Last Update
October 7 2025
Active Locations (1)
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1
Pirogov National Medical and Surgical Cente
Moscow, Russia, 105203