Status:

ACTIVE_NOT_RECRUITING

Evaluating the Clinical Utility of Modified Ventilator-Associated Event Criteria in Predicting ICU Mortality and Ventilator Duration: Can Less Restrictive Definitions Improve Prediction?

Lead Sponsor:

Benha University

Conditions:

Ventilator-Associated Events

Eligibility:

All Genders

18+ years

Brief Summary

Study design: A prospective observational study * Study setting: The study will be carried out in the department of critical care medicine, Benha university hospitals. * Study time: The study time is...

Detailed Description

Technical design: * Study design: A prospective observational study * Study setting: The study will be carried out in the department of critical care medicine, Benha university hospitals. * Study tim...

Eligibility Criteria

Inclusion

  • Adult patients (age ≥ 18 years) undergoing mechanical ventilation for ≥ 48 hours.
  • Patients admitted to ICU for
  • medical
  • trauma
  • surgical conditions.

Exclusion

  • Age below 18 years.
  • extracorporeal life support (ECLS).
  • Incomplete or inconsistent daily monitoring data.
  • Patients with confirmed or suspected respiratory viral infections (e.g., influenza, COVID-19).
  • undergoing palliative care or with a do-not-intubate (DNI) status.
  • Pregnant patients due to altered physiological responses.
  • Patients ventilated for less than 48 hours.
  • chronic ventilator dependency prior to ICU admission.
  • incomplete medical documentation impacting data collection or outcome analysis.
  • severe immunosuppression, such as recent bone marrow or organ transplant recipients, and those on high-dose corticosteroids.

Key Trial Info

Start Date :

March 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2026

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT07212881

Start Date

March 1 2025

End Date

March 1 2026

Last Update

October 8 2025

Active Locations (1)

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1

Benha university

Banhā, Egypt