Status:
COMPLETED
As Part of a Pilot Study, Visualization of Inflammatory Activity in Systemic Sclerosis Using CXCR4 PET/CT
Lead Sponsor:
Wuerzburg University Hospital
Conditions:
Systemic Sclerosis (SSc)
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Systemic sclerosis (SSc) is a heterogeneous clinical picture consisting of inflammatory, vasculopathic, and fibrotic changes. Initially, inflammatory changes usually occur, which result in fibrosis o...
Eligibility Criteria
Inclusion
- Confirmed diagnosis of SSc based on the 2013 ACR/EULAR criteria
- Duration of disease less than 5 years (onset of the first non-Raynaud's symptom within the last 5 years)
- Evidence of ILD on computed tomography
- Patient's ability to understand the information provided
- Patient of legal age
Exclusion
- Following autologous stem cell transplantation
- Presence of pulmonary hypertension
- Contraindications for performing a PET/CT scan - Pregnancy
- Breastfeeding
- Allergies to 68Ga-Pentixafor
- Patient's inability to understand and give informed consent
Key Trial Info
Start Date :
January 31 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 31 2025
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT07212959
Start Date
January 31 2024
End Date
May 31 2025
Last Update
October 8 2025
Active Locations (1)
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1
University Hospital Würzburg
Würzburg, Bavaria, Germany, 97078