Status:

ACTIVE_NOT_RECRUITING

Incidence of Graves' Disease After COVID-19 Vaccination

Lead Sponsor:

Laura ICONARU

Conditions:

Graves Disease

Eligibility:

All Genders

18+ years

Brief Summary

It is well known that an infection can be a triggering factor for the development of autoimmune thyroid disease. The COVID-19 pandemic was an example of this, with several reports of both subacute thy...

Eligibility Criteria

Inclusion

  • All patients who developed 'de novo' Graves' disease between March 2020 (the beginning of the COVID-19 epidemic in Belgium) and October 2022.

Exclusion

  • Pregnancy
  • Pre-existing Graves' disease (before March 2020)
  • Diagnosis of other thyroid disease, such as subacute or painless destructive thyroiditis
  • Use of thyroid-interfering drugs, such as lithium, amiodarone or immune checkpoint inhibitor therapy

Key Trial Info

Start Date :

November 8 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2025

Estimated Enrollment :

161 Patients enrolled

Trial Details

Trial ID

NCT07213141

Start Date

November 8 2022

End Date

December 31 2025

Last Update

October 8 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

CHU St Pierre

Brussels, Belgium, 1000

2

CHU Brugmann

Brussels, Belgium, 1020

3

UZ Brussel

Jette, Belgium, 1090