Status:

NOT_YET_RECRUITING

CHAMPION: Combining HIV And Meth Prevention and Treatment Interventions Optimized for HIV-Negative MSM

Lead Sponsor:

University of California, San Diego

Collaborating Sponsors:

National Institute on Drug Abuse (NIDA)

University of California, San Francisco

Conditions:

PrEP Adherence

Methamphetamine Use Disorder

Eligibility:

MALE

18-40 years

Phase:

NA

Brief Summary

The goal of this randomized controlled trial is to pilot test new mobile health (mHealth) interventions to improve PrEP adherence among HIV-negative men who have sex with men (MSM) with mild to modera...

Detailed Description

The CHAMPION (Combining HIV And Meth Prevention and Treatment Interventions Optimized for HIV-Negative MSM) study, a randomized controlled trial that aims to pilot test state-of-the-art multi-modal ph...

Eligibility Criteria

Inclusion

  • HIV-negative
  • Cis-gender male
  • Age 18-40 years old
  • Mild or moderate MUD (by DSM-5 SCID criteria)
  • Anal intercourse with one or more male partners in the past 6 months
  • Started daily oral PrEP more than 30 days ago and self-reported not always taking PrEP as prescribed in the past 30 days (consistent with PrEP It! inclusion criteria)
  • Willingness to participate in an mHealth study with a 6-month follow-up
  • Residing in San Diego or San Francisco County

Exclusion

  • Residing outside of San Diego or San Francisco County
  • Any condition that, in the principal investigator's judgment interferes with safe study participation or adherence to study procedures
  • Not able/willing to complete virtual/remote visits
  • Not willing to learn to self-collect dried blood spots using a finger stick

Key Trial Info

Start Date :

October 22 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 15 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT07213258

Start Date

October 22 2025

End Date

August 15 2026

Last Update

October 8 2025

Active Locations (1)

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1

Center on Substance Use and Health

San Francisco, California, United States, 94102