Status:
RECRUITING
Modification of Threat Interpretation Bias to Reduce Anxiety in Neurodegenerative Movement Disorders (Aim 3)
Lead Sponsor:
University of Virginia
Collaborating Sponsors:
National Institute of Nursing Research (NINR)
Conditions:
Huntington Disease
Parkinson Disease
Eligibility:
All Genders
21+ years
Phase:
NA
Brief Summary
The purpose of this study is to assess preliminary efficacy of a tailored cognitive bias modification for interpretation (CBM-I) app for reducing anxiety in Huntington's disease and Parkinson's diseas...
Detailed Description
The investigators will conduct a pilot randomized controlled trial of the MindTrails-Movement CBM-I app in patients with Huntington's disease and Parkinson's disease (N=136). Participants randomly ass...
Eligibility Criteria
Inclusion
- Clinical diagnosis of Huntington's disease or Parkinson's disease (genetic diagnosis of HD also acceptable)
- With anxiety symptoms (NeuroQoL Anxiety ≥12)
Exclusion
- Cognitive decline precluding ability to consent or complete the intervention (MoCA 5 min/telephone ≤11)
- Unable to read and understand English
- Does not have regular access to an internet-connected device, capable of downloading and installing the mobile application (i.e., tablet or iPhone running iOS 10 or later or an Android phone running Android 5.0 or later)
- Not located in the USA
- \<21 years old
- Active suicidality based on the answer "yes" to questions 4, 5, or 6b of the Columbia-Suicide Severity Rating Scale (Screen version)
Key Trial Info
Start Date :
November 20 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2026
Estimated Enrollment :
136 Patients enrolled
Trial Details
Trial ID
NCT07213648
Start Date
November 20 2025
End Date
September 1 2026
Last Update
November 21 2025
Active Locations (1)
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1
Univeristy of Virginia School of Nursing
Charlottesville, Virginia, United States, 22903