Status:

RECRUITING

LT Comparative Effectiveness of 2 Caries Treatments

Lead Sponsor:

Case Western Reserve University

Collaborating Sponsors:

Patient-Centered Outcomes Research Institute

Conditions:

Dental Caries

Eligibility:

All Genders

62+ years

Phase:

NA

Brief Summary

This study is a continuation of a cluster randomized clinical trial (cRCT) conducted in 33 publicly subsidized housing facilities/sites (HUD Section 202) and other low-income housing voucher programs ...

Detailed Description

Study Design: The original design was a cluster randomized clinical trial (RCT) in 33 publicly subsidized housing facilities/sites in NE Ohio and housing sites randomized into 2 arms in a roughly 1:1 ...

Eligibility Criteria

Inclusion

  • To be eligible to participate in this study, an individual must meet all of the following criteria:
  • Were participants in the original study from the 33 housing sites
  • Provide signed and dated long-term follow-up informed consent form
  • Willingness to stay in the LTFU study for 1 year
  • Additionally for focus groups, completed the treatment phase of the study

Exclusion

  • An individual who meets any of the following criteria will be excluded from participation in this study:
  • Sensitivity to silver or other heavy-metal ions
  • Serious life-threatening medical disease
  • Additionally, any participant with the presence of gingival/perioral ulceration or stomatitis or tooth abscess in any specific tooth will be referred to a dentist but can only be enrolled after resolution

Key Trial Info

Start Date :

October 8 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2030

Estimated Enrollment :

480 Patients enrolled

Trial Details

Trial ID

NCT07213661

Start Date

October 8 2025

End Date

January 1 2030

Last Update

November 13 2025

Active Locations (1)

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Case Western Reserve University

Cleveland, Ohio, United States, 44106