Status:

RECRUITING

Evaluation of Long-term Safety in Parkinsonian Patients With Intracerebroventricular Administration of A-dopamine (Anaerobic Dopamine)

Lead Sponsor:

University Hospital, Lille

Collaborating Sponsors:

InBrain Pharma

Conditions:

Parkinson Disease

Eligibility:

All Genders

18-80 years

Phase:

PHASE1

PHASE2

Brief Summary

Patients included in DIVE I have been receiving this treatment for several years as part of their participation in the study, which is scheduled to end on September 30, 2025. In this context, Lille Un...

Eligibility Criteria

Inclusion

  • Patients included in the DIVE I study still being treated with A-dopamine.
  • Social security beneficiary.
  • Able to give free and informed consent to participate in the research.
  • Patient willing to comply with all study procedures and duration.
  • Patient not planning to change their lifestyle (nutritionally, physically, and socially) during their participation in the study.

Exclusion

  • Patients not included in DIVE I and not treated with A-dopamine.
  • Presence of another serious condition that is life-threatening in the short or medium term, malnourished or cachectic patients.
  • Taking treatments containing guanethidine or its relatives, or non-selective and selective monoamine oxidase A inhibitors (iproniazid, moclobemide, toloxatone)
  • Patients already participating in another therapeutic trial involving the use of an experimental drug other than DIVE I or in an exclusion period
  • Isolated patients, defined as those without a caregiver present for at least 3 hours/day at the patient's home

Key Trial Info

Start Date :

October 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 30 2025

Estimated Enrollment :

1 Patients enrolled

Trial Details

Trial ID

NCT07214285

Start Date

October 1 2025

End Date

October 30 2025

Last Update

October 14 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

UHLillle

Lille, Haut de France, France, 59000