Status:
COMPLETED
Spinal Versus General Anesthesia and Inflammatory Response Measured by Delta Neutrophil Index in Total Knee Arthroplasty: An Observational Study
Lead Sponsor:
Elazıg Fethi Sekin Sehir Hastanesi
Conditions:
Inflammatory Response in Total Knee Arthroplasty
Eligibility:
All Genders
18-99 years
Brief Summary
This study aims to compare the effects of spinal versus general anesthesia on the inflammatory response measured by Delta Neutrophil Index (DNI) in patients undergoing total knee arthroplasty. The stu...
Detailed Description
This prospective observational study will be conducted at Elazig Fethi Sekin City Hospital, Department of Anesthesiology and Reanimation. Patients undergoing total knee arthroplasty will be assigned t...
Eligibility Criteria
Inclusion
- Patients scheduled for total knee arthroplasty
- Age ≥ 18 years
- ASA physical status classification I-III
Exclusion
- Active infection
- Hematologic disease (e.g., leukemia, aplastic anemia)
- Autoimmune or chronic inflammatory disease
- Use of corticosteroids or immunosuppressive drugs
- Malignancy
- Acute trauma or sepsis
- Pregnancy
Key Trial Info
Start Date :
September 22 2025
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 22 2025
Estimated Enrollment :
84 Patients enrolled
Trial Details
Trial ID
NCT07214558
Start Date
September 22 2025
End Date
October 22 2025
Last Update
November 26 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Health Sciences, Elazığ Fethi Sekin City Hospital
Elâzığ, Merkez, Turkey (Türkiye), 23200