Status:
NOT_YET_RECRUITING
A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention Among Emerging Adults
Lead Sponsor:
Massachusetts General Hospital
Collaborating Sponsors:
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Conditions:
Alcohol Use Disorder
Eligibility:
All Genders
18-29 years
Phase:
NA
Brief Summary
American emerging adults (EAs; aged 18-29 years) have the highest rates of alcohol use disorder (AUD) and the lowest levels of treatment engagement of any age group. Innovative, scalable, and cost-eff...
Detailed Description
This feasibility and acceptability study will develop, validate, and conduct a Phase I single-arm open trial of a large language model (LLM)-based chatbot-delivered brief intervention designed to redu...
Eligibility Criteria
Inclusion
- 18-29 years old
- Engaged in past-month hazardous drinking (consuming ≥ 5/4 drinks for men/women on two or more occasions in the past month) or exceeded recommended guidelines for risky drinking (\> 14/7 drinks per week for men/women)
- Able to read and comprehend English at a 5th grade level
Exclusion
- Report a history of or active psychosis
- Previous or current engagement in alcohol or drug treatment
- Risk for alcohol withdrawal as evidenced by very heavy weekly drinking reports on the alcohol screener (\> 40 standard drinks in a typical week in the past month)
- Demonstrate inability or unwillingness to attend in-person office visits
- Demonstrate inability or unwillingness to identify an emergency contact who could be contacted in case the participant becomes lost to follow-up
Key Trial Info
Start Date :
June 1 2027
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2028
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT07214831
Start Date
June 1 2027
End Date
August 31 2028
Last Update
October 22 2025
Active Locations (1)
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1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114