Status:

RECRUITING

Examining Heavy Metal Exposure and Respiratory Health in Young Adult Electronic Cigarette Users

Lead Sponsor:

Ohio State University Comprehensive Cancer Center

Conditions:

Heavy Metal Exposure From Vaping

Eligibility:

All Genders

18-29 years

Brief Summary

This study investigates heavy metal exposure in young adults who use electronic cigarettes.

Detailed Description

PRIMARY OBJECTIVES: I. Identify and quantify heavy metals (HM) concentration in the saliva of e-cigarette users. II. Examine changes in pulmonary functioning and HM concentration pre/post vaping. I...

Eligibility Criteria

Inclusion

  • Aged 18-29 years
  • Established electronic cigarette (EC) user (participant uses ECs on a daily/weekly basis \[used on ≥ 5 days in past 30-days\] for the past 3 months)
  • Willing to abstain from nicotine for at least 12 hours before the laboratory visit
  • Willing to not eat food or drink water/beverages for at least 30 minutes before the laboratory visit \[required for salivary collection\]
  • Utilize 4th generation EC products (pod-mod or disposable EC products; e.g., JUUL, Hyde)
  • Must be able to read and write in English

Exclusion

  • Recently COVID-19+ (defined as a positive test in the past 30 days) or a recent COVID-19 hospitalization (within the past 6 months)
  • Attempting to quit the use of ECs
  • Past 30-day use of other tobacco products (e.g., combustible cigarettes)
  • Is pregnant, planning on becoming pregnant and/or breastfeeding \[will be verified using a urine pregnancy test\]
  • Self-reported severe or significant psychological and/or psychiatric conditions \[e.g., not currently receiving treatment/medication; only past and/or stable conditions will be allowed\]
  • A history of cardiac events and/or distress within the past 3 months
  • Diagnosed with a chronic, serious lung disease or current infection (e.g., pneumonia, pulmonary edema)
  • Are deaf, hard of hearing, or have a severe motor disability

Key Trial Info

Start Date :

October 22 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 31 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT07215065

Start Date

October 22 2025

End Date

May 31 2026

Last Update

October 24 2025

Active Locations (1)

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1

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, United States, 43210