Status:
NOT_YET_RECRUITING
Metformin Versus Chlorhexidine Gel as Adjuncts to Scaling and Root Planing in Stage II Grade B Periodontitis
Lead Sponsor:
Kafrelsheikh University
Conditions:
Stage II, Grade B Periodontitis
Chronic Periodontitis
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
This clinical trial is designed to evaluate two locally delivered gels, metformin and chlorhexidine, as adjunctive therapies to scaling and root planing (SRP) in patients with Stage II, Grade B period...
Detailed Description
This is a randomized, controlled, single-blind clinical trial conducted at the Department of Oral Medicine, Periodontology, Oral Diagnosis, and Oral Radiology, Faculty of Dentistry, Kafrelsheikh Unive...
Eligibility Criteria
Inclusion
- Adults aged 18-60 years.
- Diagnosis of Stage II, Grade B periodontitis.
- Probing pocket depths ≤ 5 mm with clinical attachment loss of 3-4 mm in selected sites.
- Generally healthy individuals without systemic conditions affecting periodontal health.
Exclusion
- Current smokers or users of tobacco products.
- Pregnant or lactating women.
- Known allergy to metformin or chlorhexidine.
- Use of antibiotics or anti-inflammatory drugs within the past 3 months.
- History of periodontal therapy within the past 6 months.
Key Trial Info
Start Date :
October 6 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT07215156
Start Date
October 6 2025
End Date
June 1 2026
Last Update
October 10 2025
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