Status:

COMPLETED

Ashwagandha Extract for Weight and Stress Management in Overweight and Obese Adults

Lead Sponsor:

SF Research Institute, Inc.

Conditions:

Weight Management

Stress

Eligibility:

All Genders

19-65 years

Phase:

NA

Brief Summary

This study is designed to evaluate the effects of KSM-66 Ashwagandha root extract (300 mg daily) on weight management and stress reduction in overweight and obese adults. Ashwagandha (Withania somnife...

Detailed Description

This randomized, double-blind, placebo-controlled clinical study is being conducted to investigate the potential efficacy and safety of KSM-66 Ashwagandha® root extract (300 mg per capsule) in promoti...

Eligibility Criteria

Inclusion

  • Healthy adult men and women participants ≥ 19 years and ≤65 years of age.
  • Willingness to follow the protocol requirements as evidenced by written informed consent.
  • Participants willing to give meaningful, written informed consent prior to participation in the trial, in accordance with regulatory requirements.
  • Participants who agree to take investigational product (i.e., Till Week 8).
  • Participants with Body mass index between 25 and 39.9 kg/m2

Exclusion

  • History of Alcohol or smoking abuse.
  • History of hypersensitivity to Ashwagandha
  • Taking nutritional or energy supplements, medication, or steroids,
  • Any history of drug abuse
  • Having any clinical abnormalities
  • Simultaneously participating in any other clinical trial or participated in the past three months
  • Participants who use medication for blood pressure, use beta-blockers, inhaled any beta-agonists, use any hormonal contraceptives, having a history of corticosteroid use within three months, participants under psychotropic medication within last 8 weeks
  • Participants diagnosed with any heart disease, diabetes, stroke, neurological disorders or depression.
  • Have clinically significant acute unstable hepatic, renal, cardiovascular, or respiratory disease that will prevent participation in the study.
  • Patients with depressive episode, panic disorder, social phobia, obsessive-compulsory disorder, alcohol dependency; schizophrenia and mania.
  • Patients with post traumatic disorder.
  • Have an established practice of meditation (as meditating for at least 20 minutes, three or more times per week) for three or more months.
  • Pregnant and lactating women
  • Participation in other clinical trials during previous 3 months
  • Any clinical condition, according to the investigator which does not allow safe fulfilment of clinical trial protocol.

Key Trial Info

Start Date :

June 17 2025

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 22 2025

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT07215455

Start Date

June 17 2025

End Date

October 22 2025

Last Update

November 6 2025

Active Locations (1)

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San Francisco Research Institute

San Francisco, California, United States, 94132