Status:

NOT_YET_RECRUITING

Prospective Evaluation of Silk Fibroin Incision Dressings in ACL Reconstruction

Lead Sponsor:

NYU Langone Health

Conditions:

Anterior Cruciate Ligament Reconstruction

Eligibility:

All Genders

14-60 years

Phase:

NA

Brief Summary

The purpose of this study is to compare the incidence of early postoperative skin complications including allergic contact dermatitis, blistering, and erythema between silk fibroin incision dressings ...

Eligibility Criteria

Inclusion

  • Age 14 to 60 years
  • Scheduled for primary or revision ACL reconstruction (ACLR)
  • Able and willing to provide informed consent (≥18 years) or assent with parental/guardian permission (ages 14-17)
  • Able and willing to comply with all study-related procedures and follow-up visits

Exclusion

  • Active dermatologic conditions at or near the surgical site (e.g., eczema, psoriasis, dermatitis, open wounds)
  • Immunocompromised state (e.g., uncontrolled HIV, ongoing chemotherapy, chronic corticosteroid therapy)
  • Known or suspected allergy or hypersensitivity to silk fibroin or cyanoacrylate adhesives
  • Uncontrolled diabetes (defined as most recent HbA1c ≥ 8.0, if available; not measured for study purposes)
  • Active tobacco use within 30 days of surgery
  • Active systemic infection at the time of enrollment

Key Trial Info

Start Date :

October 14 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2027

Estimated Enrollment :

138 Patients enrolled

Trial Details

Trial ID

NCT07217613

Start Date

October 14 2025

End Date

March 1 2027

Last Update

October 16 2025

Active Locations (1)

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NYU Langone Health

New York, New York, United States, 10016