Status:

NOT_YET_RECRUITING

Cannabis Reduction and Functional Outcomes

Lead Sponsor:

Medical University of South Carolina

Collaborating Sponsors:

National Institutes of Health (NIH)

National Institute on Drug Abuse (NIDA)

Conditions:

Cannabis Use Disorder

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study evaluates the effects of cannabis use reduction among adults diagnosed with cannabis use disorder (CUD). Participants will undergo an 8-week intervention combining motivational interviewing...

Eligibility Criteria

Inclusion

  • Age 18+
  • Urinary cannabinoid level ≥ 50 ng/mL
  • DSM-5 diagnosis of CUD (mild, moderate, or severe)
  • Willingness to attempt cannabis reduction
  • Completion of Intake Visit

Exclusion

  • Serious medical/psychiatric conditions
  • Pregnancy or breastfeeding
  • Use of cannabis in past 30 days was for medical purposes only
  • Discontinuation or reduction of cannabis use may exacerbate a pre-existing condition
  • TICS score ≤ 19

Key Trial Info

Start Date :

April 1 2026

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 30 2030

Estimated Enrollment :

176 Patients enrolled

Trial Details

Trial ID

NCT07218471

Start Date

April 1 2026

End Date

January 30 2030

Last Update

October 20 2025

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