Status:
RECRUITING
A Study to Assess the Adverse Events and How Oral Emraclidine Moves Through the Body of Healthy Elderly Adult Participants
Lead Sponsor:
AbbVie
Conditions:
Healthy Volunteer
Eligibility:
All Genders
65-85 years
Phase:
PHASE1
Brief Summary
This study is to assess how oral emraclidine moves through the body of healthy elderly adult participants, and assess adverse events, and tolerability.
Eligibility Criteria
Inclusion
- BMI is ≥ 18.0 to ≤ 32.0 kg/m2 after rounding to the tenths decimal at Screening. BMI is calculated as weight in kg divided by the square of height measured in meters.
- Body weight \> 45 kg at the time of screening and upon initial confinement.
- A condition of general good health, based upon the results of a medical history, physical examination, vital signs, laboratory profile and a 12-lead ECG.
Exclusion
- History of any clinically significant cardiac, respiratory (except mild asthma as a child), renal, hepatic, gastrointestinal, genitourinary, immunological, hematologic, neurological or psychiatric disease or disorder, or any other uncontrolled medical illness.
- History of any clinically significant sensitivity or allergy to any medication or food.
- Evidence of dysplasia or history of malignancy (including lymphoma and leukemia) other than successfully treated non-metastatic cutaneous squamous cell, basal cell carcinoma or localized carcinoma in situ of the cervix.
Key Trial Info
Start Date :
October 8 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2026
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT07219030
Start Date
October 8 2025
End Date
November 1 2026
Last Update
November 10 2025
Active Locations (4)
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1
Altasciences Clinical Los Angeles /ID# 276854
Cypress, California, United States, 90630
2
K2 Medical Research, LLC /ID# 276636
Maitland, Florida, United States, 32751
3
Clinical Pharmacology Of Miami /ID# 276856
Miami, Florida, United States, 33172
4
Acpru /Id# 276996
Grayslake, Illinois, United States, 60030