Status:
RECRUITING
Intervention for Communication Quality of Life in Primary Progressive Aphasia
Lead Sponsor:
University of Texas at Austin
Collaborating Sponsors:
National Institutes of Health (NIH)
National Institute on Aging (NIA)
Conditions:
Primary Progressive Aphasia(PPA)
Semantic Dementia
Eligibility:
All Genders
40+ years
Phase:
NA
Brief Summary
The goal of this clinical trial is to determine whether individually tailored speech-language telerehabilitation helps improve communication in people with primary progressive aphasia (PPA), a form of...
Eligibility Criteria
Inclusion
- Inclusion Criteria for Persons with PPA:
- A PPA (Gorno-Tempini et al., 2011) or "PPA-plus" (Mesulam et al., 2001) diagnosis
- MMSE score of \> 15 and must be able to produce single monosyllabic words intelligibly.
- Must speak English, Spanish or both languages (i.e., bilingual speakers of English or Spanish)
- Hearing and vision adequate for participation in teleconference meetings
- Must have a care partner available (someone who will commit to attending teleconference sessions weekly during treatment phases)
- Inclusion criteria for Care Partners:
- Partners must express willingness to attend and participate in treatment sessions including those targeting dyadic communication goals
- Partners must speak English, Spanish or both languages (i.e., bilingual speakers of English or Spanish)
- Partner's hearing and vision should be adequate for participation in teleconference meetings
- Exclusion criteria for persons with PPA:
- Other central nervous system or medical diagnosis that can account for symptoms
- Psychiatric diagnosis that can account for symptoms
- The participant and/or study partner must have basic experience using a computer.
Exclusion
Key Trial Info
Start Date :
January 3 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2027
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT07219680
Start Date
January 3 2026
End Date
August 1 2027
Last Update
November 4 2025
Active Locations (1)
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1
University of Texas
Austin, Texas, United States, 78712