Status:
RECRUITING
Training Reward Responsiveness Through Virtual Reality
Lead Sponsor:
University of California, Los Angeles
Conditions:
Positive Affect
Depression
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
The purpose of this study is to compare the effects of enhanced Virtual Reality-Reward Training (eVR-RT) with an active control condition, Virtual Reality-Memory Training (VR-MT), on positive affect a...
Detailed Description
Anhedonia, or loss of interest and pleasure in usual activities, has been relatively resistant to pharmacological and psychological treatments in the context of anxiety and depression. Newer treatment...
Eligibility Criteria
Inclusion
- At least 18 years old
- Fluent in written and spoken English
- Meet all of the following dimensional score cutoffs:
- Score on the DASS-21 depression subscale must be ≥ 8
- Score on the PANAS-P of 27 or lower
- Score on the WSAS of ≥ 11
Exclusion
- Lifetime history of bipolar disorder, psychosis, mental retardation, or organic brain damage
- Substance use disorder in the past 6 months
- Current use of psychotropic medications
- Currently pregnant or planning to become pregnant
- Self-reported frequent motion sickness
- Self-reported seizures within the last year and/or a diagnosis of epilepsy
Key Trial Info
Start Date :
July 8 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2027
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT07219875
Start Date
July 8 2025
End Date
June 1 2027
Last Update
October 22 2025
Active Locations (1)
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1
University of California, Los Angeles
Los Angeles, California, United States, 90095