Status:

ACTIVE_NOT_RECRUITING

Effects of P-TIOX and Tixel Combined on Reducing Eye Wrinkles

Lead Sponsor:

Main Line Center for Laser Surgery

Conditions:

Periocular Fine Wrinkles

Eligibility:

All Genders

30+ years

Phase:

NA

Brief Summary

This study looks at whether using a cosmeceutical called P-TIOX together with a treatment called Tixel can reduce fine lines and wrinkles around the eyes better than Tixel treatment alone. Tixel is an...

Detailed Description

This clinical trial is designed to evaluate the combined effect of a topical cosmeceutical, P-TIOX, with fractional thermal treatment using the Tixel device, on improving fine lines and wrinkles aroun...

Eligibility Criteria

Inclusion

  • Severity of 2, 3, or 4 based on the 5-point severity scale of both periocular areas
  • 30 years of age or older
  • Willingness to comply with study visits
  • Willingness to discontinue use of other topical cosmeceuticals/retinoids to the periocular region for the duration of the study

Exclusion

  • Pregnant or breastfeeding
  • Prior treatment with periocular laser, energy-based devices, neuromodulators, or dermal fillers within the past six months
  • Prior surgical intervention in the periocular region within the past twelve months
  • Use of topical retinoids in the periocular area within the past four weeks
  • Known hypersensitivity to any component of P-TIOX
  • Presence of active dermatologic or ocular disease in the treatment area
  • Active systemic infection
  • Active cold sore/herpes labialis infection

Key Trial Info

Start Date :

June 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2027

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT07222176

Start Date

June 1 2025

End Date

June 1 2027

Last Update

October 29 2025

Active Locations (1)

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1

Main Line Center for Laser Surgery

Ardmore, Pennsylvania, United States, 19107