Status:
RECRUITING
The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease
Lead Sponsor:
Brigham and Women's Hospital
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
American Heart Association (AHA)
Conditions:
Chronic Kidney Disease
Kidney Transplant
Eligibility:
All Genders
18+ years
Brief Summary
People with chronic kidney disease (CKD) often experience faster aging of the heart and blood vessels, which raises the risk of heart problems beyond traditional factors like high blood pressure or ch...
Eligibility Criteria
Inclusion
- Renal transplant candidate on the waitlist
- Age greater or equal to 45 years, or if 18-44 years of age on dialysis for 5 years or more
Exclusion
- Left ventricular ejection fraction (LVEF) \< 40%
- History of coronary artery bypass grafting (CABG)
- History of heart transplant
- Patients who undergo revascularization as a result of pre-transplant cardiac PET
Key Trial Info
Start Date :
March 10 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2030
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT07222683
Start Date
March 10 2023
End Date
July 1 2030
Last Update
October 30 2025
Active Locations (1)
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1
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115