Status:

NOT_YET_RECRUITING

Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)

Lead Sponsor:

Echosens

Collaborating Sponsors:

Syneos Health

Conditions:

Heart Failure

Heart Failure - NYHA II - IV

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This is a pivotal, global, prospective, cross-sectional, multicentric clinical investigation designed to explore a non-invasive, reliable alternative to invasive, catheter-based hemodynamic assessment...

Detailed Description

CHF, as defined by the American College of Cardiology and the American Heart Association, is "a complex clinical syndrome that results from any structural or functional impairment of ventricular filli...

Eligibility Criteria

Inclusion

  • Have read, understood, and signed the informed consent form (ICF)
  • Be ≥18 years of age at the time of screening
  • Have suspected or diagnosed acute or chronic HF and be scheduled to undergo right-sided cardiac catheterization

Exclusion

  • Inability to consent
  • Chronic liver disease (self-reported alcohol use \>14 drinks/week in females and \>21 drinks/week in males), positive hepatitis C virus serology, positive hepatitis B surface antigen, autoimmune hepatitis, hemochromatosis, or cholestatic disease)
  • BMI \>40 kg/m2
  • Fontan-type circulation
  • Ascites
  • Heart transplantation
  • Pregnancy, breastfeeding, or intent to become pregnant during the study
  • Intent to donate/bank or retrieve eggs (ova, oocytes) or donate sperm during the study

Key Trial Info

Start Date :

January 15 2026

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 15 2027

Estimated Enrollment :

149 Patients enrolled

Trial Details

Trial ID

NCT07222813

Start Date

January 15 2026

End Date

January 15 2027

Last Update

October 30 2025

Active Locations (7)

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Page 1 of 2 (7 locations)

1

Keck Medicine of USC-Norris Healthcare Center - Transplant Clinic

Los Angeles, California, United States, 90033

2

University of Minnesota

Minneota, Minnesota, United States, 55455

3

Medical University of South Carolina

Charleston, South Carolina, United States, 29425

4

University of Texas Southwestern Medical Center - Clinical Heart and Vascular Center - West Campus Building 3 Location

Dallas, Texas, United States, 75390