Status:
RECRUITING
A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer
Lead Sponsor:
City of Hope Medical Center
Conditions:
Hepatocellular Carcinoma (HCC)
Cholangiocarcinoma
Eligibility:
All Genders
18+ years
Brief Summary
Gastrointestinal (GI) cancers remain a major global health burden, largely due to the lack of effective and accessible early screening strategies. Current diagnostic approaches-including endoscopy, co...
Detailed Description
This study will establish a comprehensive, retrospective, international multi-center cohort consisting of peripheral blood samples from participants with major gastrointestinal cancers-including hepat...
Eligibility Criteria
Inclusion Criteria:
- Adults aged 18 years or older at the time of blood sample collection.
- Patients with a confirmed diagnosis of one of the following gastrointestinal cancers: Hepatocellular carcinoma (HCC), Cholangiocarcinoma (CCA), Pancreatic ductal adenocarcinoma (PDAC), Esophageal squamous cell carcinoma (ESCC), Gastric cancer (GC), Colorectal cancer (CRC), Non-cancer control participants, including healthy volunteers or patients with benign gastrointestinal conditions.
- Availability of retrospective blood samples collected according to institutional protocols.
- Willingness to allow use of de-identified clinical and demographic data for research purposes.
Exclusion Criteria:
- other active malignancies; insufficient sample quality/volume; recent chemotherapy/radiotherapy/surgery; any condition preventing reliable participation.
Key Trial Info
Start Date :
June 21 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 18 2026
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT07224750
Start Date
June 21 2024
End Date
June 18 2026
Last Update
November 26 2025
Active Locations (1)
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1
City of Hope Nat Medical Ctr
Duarte, California, United States, 91010