Status:

RECRUITING

A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)

Lead Sponsor:

Eli Lilly and Company

Conditions:

Obesity

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The purpose of this study is to evaluate tirzepatide within a real-world setting to assess body weight loss and incidence of type 2 diabetes in adults without diabetes who have obesity and at least on...

Eligibility Criteria

Inclusion

  • Have a body mass index ≥30 and ≤34.9 kilogram per square meter (kg/m2)
  • Have an increased waist to height ratio (defined by \>0.5)
  • Have at least one weight related comorbid condition
  • Have had at least one attempt to lose weight with lifestyle intervention (diet and physical activity)

Exclusion

  • Have type 1 diabetes, type 2 diabetes, or any other types of diabetes
  • Have had a change in body weight of greater than 5 kilograms (11 pounds) within 90 days prior to screening

Key Trial Info

Start Date :

November 24 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2032

Estimated Enrollment :

3000 Patients enrolled

Trial Details

Trial ID

NCT07247084

Start Date

November 24 2025

End Date

July 1 2032

Last Update

March 6 2026

Active Locations (24)

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Page 1 of 6 (24 locations)

1

P91604 St John's Medical Centre

Altrincham, United Kingdom, WA14 1PF

2

P89008 Ashton Medical Group

Ashton-under-Lyne, United Kingdom, OL6 6EW

3

Y02319 SSP Bolton General Practice

Bolton, United Kingdom, BL1 4TH

4

P83012 Tower Family Healthcare

Bury, United Kingdom, BL9 0NJ

A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK) | DecenTrialz