Status:
RECRUITING
Identifying the Optimal IMT Dose in ICU
Lead Sponsor:
Royal Brompton & Harefield NHS Foundation Trust
Conditions:
Difficult to Wean, Mechanically Ventilated Patients With a Tracheostomy
Eligibility:
All Genders
18+ years
Brief Summary
200,000 adults are admitted to intensive care in the UK each year. Many of these patients need help with their breathing and are put on a machine called a ventilator. Research shows that many patient...
Eligibility Criteria
Inclusion Criteria:
- Mechanically ventilated patients with a tracheostomy
- Aged ≥ 18 years
- Co-operative and able to participate in IMT.
- Informed consent or surrogate approval
Exclusion Criteria:
- Facial or skull fracture, or a bleeding disorder which would prohibit oesophageal catheter placement.
- Undrained pneumothorax/pneumomediastinum.
- Delirium or deep sedation that impedes the patient's ability to participate in study procedures
- Pregnancy
- Unlikely to survive, or consultant assessment that the patient is not appropriate.
- Wounds that prohibit EMG electrode placement.
Key Trial Info
Start Date :
November 23 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2027
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT07256821
Start Date
November 23 2025
End Date
January 1 2027
Last Update
January 12 2026
Active Locations (1)
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1
Royal Brompton and Harefield Hospitals
Marlow, United Kingdom, SL7 3AS