Status:

RECRUITING

Combined Method of Surgical Treatment of Anal Fissure

Lead Sponsor:

State Scientific Centre of Coloproctology, Russian Federation

Conditions:

Chronic Anal Fissure

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

The purpose of this study is to improve treatment outcomes for patients with chronic anal fissure.

Detailed Description

A chronic anal fissure is a rupture of the mucous membrane of the anal canal, lasting more than 2 months and resistant to non-surgical treatment. This condition is accompanied by a strong pain syndrom...

Eligibility Criteria

Inclusion Criteria:

  • • Patients with chronic anal fissure with spasm of anal sphincter

Exclusion Criteria:

  • • Inflammatory diseases of the colon

    • Pectenosis
    • Previous surgical interventions on the anal canal
    • IV grade internal and external hemorrhoids
    • Rectal fistula
    • Severe somatic diseases at the decompensation stage
    • Pregnancy and lactation
    • Anal sphincter insufficiency
    • Chronic paraproctitis
    • Individual intolerance and hypersensitivity to botulinum toxin
    • Myasthenia gravis and myasthenic syndromes
    • History of allergic reaction to anticoagulants.
    • Blood diseases (thrombocytopenia, splenomegaly, etc.)

Key Trial Info

Start Date :

September 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2026

Estimated Enrollment :

122 Patients enrolled

Trial Details

Trial ID

NCT07268261

Start Date

September 1 2023

End Date

September 1 2026

Last Update

December 5 2025

Active Locations (1)

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1

SSCCRussia

Moscow, Russia, 123423