Status:
RECRUITING
Alii Supplement Study
Lead Sponsor:
Texas Christian University
Conditions:
Nutrient Deficiency
Happiness
Eligibility:
FEMALE
18-25 years
Phase:
PHASE2
Brief Summary
The goal of this clinical trial is to learn if the Alii Supplement can be used to reduce symptoms related to nutritional depletion in hormonal birth control pill users. The main questions it aims to a...
Detailed Description
This randomized, double-blind clinical trial will look to examine the efficacy of the Alii supplement, compared to a placebo, on reducing symptoms related to nutritional depletion in hormonal birth co...
Eligibility Criteria
Inclusion Criteria:
- Participants must be on the hormonal birth control pill as the investigators are testing the effectiveness of a supplement for women who take the hormonal birth control pill
- Participants must be willing to complete a follow up survey as this study will be multiple parts
- Participants must be willing to take a daily supplement as this study is testing how a supplement influences a variety of psychological outcomes
- Participants must be on the hormonal birth control pill for at least six months as participants who have been on the pill for less than 6 months may not be experiencing nutritional depletion yet
- If the investigators are able to do so, the investigators will only recruit participants who take the one-month hormonal birth control pill rather than the three month hormonal birth control pill, as the investigators are going to have participants come in after 28 days (day 2 of pack 1 and day 2 of pack 2) and participants on the three-month HBC pill may be on a 21 day cycle.
- Participants must have no food or medication allergies that will prevent the participants from safely taking the supplement
- Participants must not be taking any vitamins or participant must report willingness to abstain from taking vitamins during the study as individuals who are already taking vitamins may not be experiencing nutritional depletion associated with hormonal birth control
- If the investigators have the ability to do so, the investigators will only recruit participants who are not taking medications. Participants on various medications (e.g., SSRIs, ADHD medications, etc.) may report differing psychological states due to their medications, rather than the supplement. Therefore, it would be best to exclude those individuals if possible.
Exclusion Criteria:
- Participants cannot be naturally cycling as the investigators are testing a supplement for women on hormonal birth control
- Participants cannot be unwilling to complete a follow up study because this is a multi-part study
- Participants cannot be unwilling to take a supplement because the study centers around taking a supplement
- Participants cannot be on the hormonal birth control pill for less than 6 months as participants who have been on the pill for less than 6 months may not be experiencing nutritional depletion yet
- If the investigators are able to do so, participants cannot take the three month hormonal birth control pill, as the investigators are going to have participants come in after 28 days (day 2 of pack 1 and day 2 of pack 2) and participants on the three-month HBC pill may be on a 21 day cycle.
- Participants cannot have any food or medication allergies that will prevent the participants from safely taking the supplement
- Participants must not be taking any vitamins or participants must report willingness to abstain from taking vitamins during the study as individuals who are already taking vitamins may not be experiencing nutritional depletion associated with hormonal birth control
- If the investigators have the ability to do so, the investigators will only recruit participants who are not taking medications. Participants on various medications (e.g., SSRIs, ADHD medications, etc.) may report differing psychological states due to their medications, rather than the supplement. Therefore, it would be best to exclude those individuals if possible.
Key Trial Info
Start Date :
January 12 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 29 2026
Estimated Enrollment :
68 Patients enrolled
Trial Details
Trial ID
NCT07271316
Start Date
January 12 2026
End Date
April 29 2026
Last Update
January 14 2026
Active Locations (1)
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1
Texas Christian University
Fort Worth, Texas, United States, 76109