Status:
RECRUITING
A Study to Evaluate Patient-Reported Satisfaction, Effectiveness, and Safety of Atezolizumab in Participants Treated in Routine Clinical Practice
Lead Sponsor:
Hoffmann-La Roche
Conditions:
Lung Cancer, Hepatocellular Carcinoma
Eligibility:
All Genders
18+ years
Brief Summary
This is a non-interventional, multi-country, multi-centre, multicohort, primary data collection study, designed to assess patients' reported satisfaction with Atezolizumab Subcutenous (SC) treatment a...
Eligibility Criteria
Inclusion
- Participants must have one of the following confirmed diagnoses for which atezolizumab is approved in the local SmPC:
- Early stage NSCLC following complete resection and platinum-based chemotherapy with a high risk of recurrence and PD-L1 expression on ≥ 50% of TC and with no EGFR-mutant or ALK-positive NSCLC
- Metastatic stage NSCLC with PD-L1 expression on ≥ 50% TC or ≥ 10% tumor infiltrating immune cells (IC) and with no EGFR-mutant or ALK-positive NSCLC not previously treated
- Extensive-stage small cell lung cancer (ES-SCLC) not previously treated
- Advanced or unresectable HCC not previously treated with systemic therapy
- Should not have received \> 4 prior cycles of IV Atezolizumab
Exclusion
- Not receiving treatment with Atezolizumab according to standard of care and in line with the current SmPC or local labelling
- Receiving concomitant systemic anticancer therapy at the time of initiation of Atezolizumab or an Atezolizumab-containing regimen for treatment of the same disease, as per label
- Receiving treatment with Atezolizumab as part of a clinical trial, pre-approval access program, compassionate use program, expanded use program, post-trial access program, or continued access program
- Unwilling to complete questionnaires related to treatment satisfaction and treatment-related quality of life
Key Trial Info
Start Date :
July 17 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2028
Estimated Enrollment :
700 Patients enrolled
Trial Details
Trial ID
NCT07284121
Start Date
July 17 2025
End Date
December 31 2028
Last Update
February 27 2026
Active Locations (85)
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1
Landesklinikum Krems
Krems, Austria, 3500
2
Ordensklinikum Linz Elisabethinen
Linz, Austria, 4020
3
Krankenhaus Nord - Klinik Floridsdorf
Vienna, Austria, 1210
4
Klinikum Wels-Grieskirchen
Wels, Austria, 4600