Status:
RECRUITING
Analysis of the Specificity and Persistence of Nasal Immune Responses to Respiratory Viral Antigens in Immunocompromised and Healthy Cohorts
Lead Sponsor:
Fondazione IRCCS Policlinico San Matteo di Pavia
Conditions:
Immuno-modulation
Immuno-suppression
Eligibility:
All Genders
18-90 years
Brief Summary
The goal of this observational study is to characterize nasal mucosal immunity to respiratory viruses, such as SARS-CoV-2, in immunocompromised individuals and healthy volunteers. The study involves ...
Eligibility Criteria
Inclusion Criteria:
- Informed Consent: Participants must have signed an informed consent form.
- Age Range: Participants aged between 18 and 90 years.
- Healthy Immunocompetent Donors: no underlying medical conditions declared, no clinical history of immunodeficiency or use of immunosuppressive medications.
- Immunocompromised Patients: subjects with medical conditions or treatments associated with significant impairment of the immune system. This may include organ or stem cell transplants, ongoing immunosuppressive therapies, documented genetic immunosuppression.
Exclusion Criteria:
- Pregnant or lactating women.
- Individuals unable to provide informed consent
Key Trial Info
Start Date :
September 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 30 2027
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT07295535
Start Date
September 1 2025
End Date
September 30 2027
Last Update
December 19 2025
Active Locations (1)
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1
Fondazione IRCCS Policlinico San Matteo di Pavia
Pavia, Pavia, Italy, 27100